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Bone Marrow Transplant

Alternate Names

  • BMT

Definition

Bone marrow is a spongy tissue found in the center of many bones in the human body. The following bones contain either the red or yellow form of bone marrow:
  • upper arm
  • lower leg
  • ribs
  • breast bone
  • vertebra of the spine
  • Who is a candidate for the procedure?

    Conditions that may benefit from a bone marrow transplant include the following:
    • aplastic anemia, a condition in which damaged or destroyed stem cells in the bone marrow limit production of red blood cells
    • bone marrow depression, where the bone marrow has been damaged by treatments such as chemotherapy or radiation therapy
    • a variety of cancers, especially the blood cancers called leukemia and lymphoma
    • inherited blood disorders, such as thalassemia
    • some immunodeficiency disorders, such as severe combined immunodeficiency syndrome, a rare inherited condition
    • inherited enzyme deficiency conditions such as Hurler's syndrome

    How is the procedure performed?

    Sources

    The Merck Manual, 17th Edition, 1999, Beers, et al.

    Professional Guide to Diseases, 6th Edition, 1998, Holmes, et al.

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