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Obesity

Definition

Obesity is measured using body mass index, abbreviated as BMI. BMI is determined by dividing a person's weight in kilograms by a person's height in meters squared. A person whose BMI is 25.0 to 26.9 is considered overweight, while a BMI of 27.0 to 29.9 kg/m2 is considered extreme overweight. A BMI of 30 to 39.9 kg/m2 indicates obesity. A BMI of 40 kg/m2 or more indicates extreme or morbid obesity.

What is going on in the body?

Food is made up of calories, or units of energy. Physical activity and normal body metabolism burn calories. When a person takes in more calories than the body uses, the extra calories are stored as fat. These fat cells enlarge or decrease in size depending on the balance of energy in the body. When fat cells build up or accumulate, it causes obesity.

Symptoms

What are the signs and symptoms of the condition?

Someone who is obese has accumulations of body fat. Other symptoms may be seen if the fat affects other body systems. For example, an obese person may have swelling in the legs because the heart has to work harder.

Risks

What are the causes and risks of the condition?

Obesity is a complex condition. It is caused by an interaction among a number of factors. These varied factors fit into these categories: behavioralculturalgeneticmetabolicphysiologicalsocial

Prevention

What can be done to prevent the condition?

Staying at normal body weight by eating healthfully and keeping physically active can usually prevent obesity.

Diagnosed

How is the condition diagnosed?

Diagnosis of obesity begins with a medical history and physical exam. The National Institutes of Health (NIH) recommend that healthcare professionals follow these steps: measure height and weightdetermine the person's body mass indexmeasure waist circumferenceassess comorbidities, that is, additional risk factorsuse the treatment algorithm to see if the person should be treated for obesitydetermine whether the person is ready and motivated to lose weight

Waist circumference

The amount of fat around the abdomen is very important in assessing disease risk. An individual's risk for certain disorders increases when waist circumference is larger than normal. These disorders include: coronary heart diseasehigh blood pressuretype 2 diabetes

A waist measurement of more than 40 inches, or 102 cm, in men and more than 35 inches, or 88 cm, in women is above normal. Combined with overweight or obesity, a high waist circumference can raise the person's disease risks from high to extremely high.

Comorbidities

Some disorders place a person at high absolute risk for death if they are combined with obesity. An obese person with one or more of these factors should be treated aggressively. These factors include: atherosclerotic diseases, such as peripheral arterial disease and carotid artery disease that causes symptomscoronary artery disease, including a history of heart attack or heart bypass surgerysleep apneatype 2 diabetes

Other comorbidities increase an obese person's risk of death but are not life-threatening. These factors, which should be treated, include: gallstonesgynecological problems, such as amenorrheaosteoarthritisstress incontinence

A third set of comorbidities also increases an obese person's risk of death if they are combined. Three or more of these factors increase a person's high absolute risk: an age of 45 or older in menan age of 55 or older in womencigarette smokingfamily history of early heart diseasehigh blood pressure, or current treatment with medicines to lower blood pressurehigh LDL, that is, "bad" or "lethal" cholesterolimpaired fasting blood glucose levelslow HDL, that is, "good" or "healthy" cholesterol

Treatment algorithm

The treatment algorithm developed by NIH helps the provider decide if treatment for obesity is appropriate. It takes into account the person's BMI, waist circumference, and comorbidities.

Readiness and motivation

The healthcare professional needs to ask questions to see if the person is ready and motivated to lose weight. These questions deal with the following issues: attitudes toward physical activitypotential barriers to the person's adoption of changeprevious attempts at weight lossreasons and motivation for weight losssupport expected from family and friendstime availabilityunderstanding of risk and benefits

Long Term Effects

What are the long-term effects of the condition?

Obesity puts a person at risk for other health problems, including: back painbreathing problemscertain types of cancercoronary heart diseasediabetesgallbladder diseasehigh blood pressureosteoarthritisstroke

Obesity can even lead to an early death. As obesity increases, the risk for these problems also increases.

Other Risks

What are the risks to others?

Obesity is not contagious. It poses no risk to others.

Treatments

What are the treatments for the condition?

NIH recommends weight loss treatment for people who have one or more of the following conditions: a BMI between 25 and 29.9 and two or more risk factorsa BMI of 30 or highera high-risk waist circumference and two or more risk factors

The first weight loss goal should be a 10% weight loss over a 6-month period. The rate of weight loss should be 1 to 2 pounds a week. Faster weight loss does not improve the long-term results. After the first 6 months, additional weight management goals can be discussed with the healthcare professional. Sometimes more weight loss is needed. Others may be ready to maintain their weight loss.

No one treatment works for everyone. The healthcare professional should follow these guidelines in planning treatment: know how the treatment fits into other healthcare and self-care needs of the personmake changes based on the person's preferences and responsesset weight loss goals with the individualschedule regular office visits to track and support weight loss

A successful weight management plan will include the following components: behavior therapydietary therapyregular physical activity

The plan may also include medicines or surgery.

Dietary therapy

Dietary therapy is works best when it meets the needs of the individual. NIH recommends the following general dietary guidelines. A diet with 1,000 to 1,200 calories a day is appropriate for most women.A diet with 1,600 calories a day is appropriate for most men.A diet with 1,600 calories a day may be appropriate for women who exercise regularly or weigh over 165 pounds.A 1,200-calorie diet may be recommended for a person who is not losing weight on a 1,600-calorie diet.If a person is hungry, the healthcare provider may recommend adding 100 to 200 calories a day.Specific dietary recommendations should be given to be sure the person gets enough essential nutrients.

Physical activity

To begin treatment of obesity, NIH recommends moderate levels of physical activity 30 to 45 minutes a day, 3 to 5 days a week. The activity should be started slowly and gradually increased in intensity. Some moderate physical activities are as follows: bicycling 5 miles in 30 minutesgardening for 30 to 45 minutesraking leaves for 30 minuteswalking 2 miles in 30 minuteswater aerobics for 30 minutes

Behavior therapy

Behavior therapy provides ways to overcome barriers to dietary therapy or physical activity. A good behavior therapy plan has the following characteristics: incorporates the person's attitudes, beliefs, and historyincludes a partnership with the healthcare providersets reasonable goalsincludes self-monitoring, with appropriate rewardsfocuses on what mattersincludes frequent contact with the healthcare provider

Medication

The Food and Drug Administration (FDA) has approved only two medications for long-term use for weight loss. They are orlistat (i.e., Xenical), and sibutramine (i.e., Meridia). These medicines are recommended for people with a BMI of 27 to 29.9 with comorbidities. NIH also includes them as a consideration for people with a BMI of 30 or higher. As of 2007, the FDA is recommending the orlistat be made available over-the-counter, without a prescription.

Three other medications - diethylpropion (i.e., Tenuate), phendimetrazine (i.e., Bontril, Plegine, Prelu-2, X-Trozine, Adipost), and phentermine (i.e., Adipex-P, Fastin, Ionamin, Oby-trim, Pro-Fast, Zantryl) are FDA approved for short term (a few weeks) use only. They function as appetite suppressants.

Bariatric SurgeryThe principle of this surgery is to alter the digestive tract in such a way that either restricts the amount of food a person can eat at a time, through smaller stomach size, or routes much of the calorie content out of the body rather than letting it be absorbed. This surgery has become more popular and more successful in recent years.

NIH includes bariatric surgery as an option for people with a BMI or 40 or higher, or 35 or higher with comorbidities. An individual must be willing to make major lifestyle changes, including the timing and content of meals, exercise, vitamin and mineral supplementation, and rigorous medical follow-up.

Tools NIH provides sample tools to aid in weight management. These include the following: dietary informationguide to behavior changeguide to physical activityweekly food and activity diaryweight and goal records

Contraindications NIH states that these groups of people should be excluded from weight loss treatment: women who are pregnant or breastfeedingpeople with a serious uncontrolled psychiatric illness, such as major depressionindividuals with serious illnesses that might be worsened by calorie restriction

NIH also recommends that certain individuals be referred to specialists for weight loss as needed. These include people with a history of eating disorders, such as anorexia nervosa or bulimia. People who are currently abusing drugs should also be referred to a specialist.

Side Effects

What are the side effects of the treatments?

Losing weight is not risk-free. Diets that are not carefully planned increase the risk of vitamin deficiencies. Rapid weight loss can cause nausea, tiredness, weakness, hair loss, and low blood pressure. Dieting can also lead to emotional changes and binge eating. Medicines may cause increased blood pressure and heart rate, decreased absorption of fat soluble vitamins, and loose stools. Surgery for weight loss has all the risk of any major surgery. Nutrient deficiencies can also occur if parts of the digestive system are bypassed.

After Treatment

What happens after treatment for the condition?

After the person has reached the weight loss goal, weight maintenance needs to be lifelong. The person should have regular treatment to continue with these measures: behavior therapydietary therapyregular physical activity

The ongoing therapy can be given in a number of ways. Some options recommended by NIH include: e-mail remindersgroup meetingsregular visits with the healthcare professionaltelephone communications

Weight loss in an obese person can have the following effects: lower blood pressure in those with high blood pressurelower elevated blood glucose levels in people with diabeteslower elevated cholesterol, LDL cholesterol, and triglyceride levelsincrease low levels of HDL cholesterol

While these effects are beneficial, they may also signal a need for a change in medicines. For example, the person may need lower doses of a medicine to lower blood pressure. Other people may need different medicines or be able to stop medicine completely for elevated blood glucose levels.

Monitor

How is the condition monitored?

After successful treatment for obesity, the person can check his or her weight regularly. The individual also needs to make regular visits to the healthcare professional. NIH recommends an appointment at 6 months and again one year after the start of the weight management plan. The healthcare professional will look at the person's weight, BMI, and waist circumference during these visits. Any new or worsening symptoms should be reported.