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  • Cellulitis


Cellulitis is an infection of the skin and the layer of tissue under the skin.

What is going on in the body?

Cellulitis most often develops on the legs but can be seen on the face and on any other skin on the body. Usually, it affects a relatively large area of skin. Cellulitis is usually due to an infection of the skin with bacteria, but it may also be caused by a fungus.


What are the causes and risks of the infection?

Cellulitis is usually caused by a break in the skin that becomes infected with bacteria or fungi. It can occur in wounds caused by injury and in surgical wounds. Sometimes, however, it can occur when there is no obvious break in the skin.
Risk factors for cellulitis include:
  • recent surgery
  • diabetes
  • recentchickenpoxinfection
  • immunodeficiency disorder, in which the body's infection-fighting mechanisms are impaired. People withAIDS, for example, have a significant risk of cellulitis.
  • impaired circulation, such asperipheral arterial disease, which limits blood flow to the legs and arms
  • chronic use of steroids


What can be done to prevent the infection?

Prevention of cellulitis starts with good hygiene. Any breaks in the skin, such as cuts, bites, or scratches, should be cleaned with soap and water before applying a bandage. The area should be kept clean until the skin has healed over.
People with diabetes need to be especially careful with wounds to their feet or legs. Diabetes causes nerve damage, known as neuropathy, which can result in a lack of feeling in the legs and feet. Because people with diabetes may not be aware of a foot injury, they should inspect their feet daily for any cuts or abnormal areas. Diabetes also causes poor circulation, which means wounds do not heal well. As a result, cellulitis is more difficult to treat in people with diabetes.


How is the infection diagnosed?

Cellulitis is usually obvious from the medical history and physical examination, but the underlying cause is not necessarily obvious. Further tests depend on what is suspected. In some cases, more detailed examination, special X-rays, or other tests may be used to look for the possibility of a deeper, more serious infection, such as necrotizing fasciitis, an infection of the tissue layers between and around the muscles, or osteomyelitis, an infection of the bone.

Long Term Effects

What are the long-term effects of the infection?

If cellulitis is not treated, it can get worse. Some cases can develop into deeper, more serious infections of the tissue under the skin. This can lead to serious effects, including loss of a limb and even death. Many cases of foot and legamputationin people withdiabetesstart out as cellulitis.

Other Risks

What are the risks to others?

Cellulitis is not contagious and poses no risk to others.


What are the treatments for the infection?

For mild, superficial infections, oral antibiotics, such as cephalexin (i.e., Keflex, Panixine DisperDose) or dicloxacillin, are often used. Over-the-counter pain medication, such as ibuprofen (i.e., Advil, Motrin) or acetaminophen (i.e., Tylenol), can be used as needed to relieve discomfort. For more severe infections, individuals may need intravenous (IV) antibiotics, such as oxacillin or nafcillin.
Cellulitis may get worse even with treatment, especially in people withdiabetes. In these cases, more aggressive treatment may be needed. This may include surgery to remove dead skin or even bone.

Side Effects

What are the side effects of the treatments?

Antibiotics and over-the-counter pain medications may cause upset stomach, rash, or allergic reactions. Surgery can be complicated by bleeding, new infections, or reactions to anesthesia.

After Treatment

What happens after treatment for the infection?

In most cases, cellulitis goes away after treatment. If treatment is successful, people can usually return to normal activities.


How is the infection monitored?

The healthcare professional will examine the area of cellulitis regularly to assess healing. In some cases, special X-ray tests may be used if a deeper infection is suspected. Any new or worsening symptoms should be reported to the healthcare professional.

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