FREE Economy Shipping! (click for details)

My Cart 0 items: $0.00



Alternate Names

  • idiopathic pulmonary hemosiderosis
  • IPH
  • pulmonary hemorrhage


Hemosiderosis is a rare, often fatal, condition in which iron builds up in the lungs. The iron is in the form of hemosiderin, a pigment in blood. Hemosiderosis results from bleeding into the lungs, also known as pulmonary hemorrhage.

What is going on in the body?

This condition usually shows up between the ages of 6 months and 20 years. Blood that leaks out of the capillaries is taken up by scavenger cells in the lung. The breakdown products of the blood irritate the lung and lead to scarring.


What are the causes and risks of the condition?

Hemosiderosis is often linked with anemia and chronic infections. It may also be caused by problems with the heart or the immune system.
Pulmonary hemosiderosis is more common in children under 10 years old and is equally common in boys and girls. When it begins in adulthood, it is more likely to affect males.


What can be done to prevent the condition?

Prevention is based on treating the underlying cause, if one can be found.


How is the condition diagnosed?

Diagnosis begins with a medical history and physical exam. Diagnostic tests may include:
  • blood tests, such as a complete blood count, or CBC, and liver function tests
  • chest x-ray
  • lung scan
  • liver scan
  • lung biopsy
  • pulmonary function tests
  • sputum culture
  • culture of stool sample
An important part of the diagnosis is to rule out known causes of bleeding into the lungs.

Long Term Effects

What are the long-term effects of the condition?

If hemosiderosis is not effectively treated, long-term effects from the bleeding and kidney damage can include:
  • glomerulonephritis, or progressive destruction of the filtering system of the kidneys
  • cirrhosis of the liver, a condition of continued scarring and decreased liver function
  • diabetes
  • heart disease
  • congestive heart failure, a condition in which the heart is not able to pump enough blood to body tissues
  • death

Other Risks

What are the risks to others?

Hemosiderosis is not contagious. If the underlying cause is an infection, that infection may be contagious.


What are the treatments for the condition?

The treatment depends on the cause. Blood transfusions may be needed for blood loss. Supplemental oxygen is given for low levels of oxygen in the blood. Corticosteroids and medications that suppress the immune system are often used. If the cause is sensitivity to cow's milk, a milk-free diet may be recommended.

Side Effects

What are the side effects of the treatments?

Side effects depend on the treatment used. Side effects of steroids may include stomach upset, jittery feelings, muscle weakness, bloating, and weight gain.

After Treatment

What happens after treatment for the condition?

Pulmonary bleeding can recur from time to time and will need to be evaluated.


How is the condition monitored?

This condition is monitored for the rest of the person's life. Any further bleeding in the lungs must be evaluated. The healthcare professional should be told about any new or worsening symptoms. Blood tests, pulmonary function tests, and chest x-rays may also help monitor the course of the disease.


[hyperLink url="" linkTitle=""][/hyperLink]

Current Pediatric Diagnosis and Treatment, Hathaway, Groothuis, Hay, Paisley, 1993.

Illustrated Guide to Diagnostic Tests, Springhouse, 1998.

Harrison's Principles of Internal Medicine, Fauci, 1998.

« Back