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Restless Leg Syndrome

Restless Leg Syndrome

Alternate Names

  • nocturnal myoclonus
  • akathisia


Restless leg syndrome involves unusual sensations in the legs that cause frequent leg movements.

What is going on in the body?

No one knows exactly why restless leg syndrome occurs. People who suffer from restless leg syndrome have uncontrollable urges to move their legs. A feeling of discomfort in the leg prompts the need for movement.
For some people, these sensations may be the result of nerve damage. The sensations may also be caused by decreased blood flow through some vessels in the legs. These leg movements often occur after a person has gone to bed, making sleeping difficult. When the urge to move the leg happens during the day, a person may have to get up and walk around to relieve the discomfort.


What are the causes and risks of the condition?

While the exact cause of restless leg syndrome is unknown, its tendency to run in families suggests a strong genetic link. In a recent study of identical twins, of 12 pairs in which one twin had restless leg syndrome, in 10 cases the other twin did as well.
Restless leg syndrome is also more common in:
  • people who are 40 years of age or older
  • individuals who are under a lot of stress
  • pregnant women, especially in the third trimester of pregnancy
  • people with disorders of nerves that supply the muscles and skin, called peripheral nerve diseases
  • people with claudication, a leg pain that occurs when the person is walking, due to poor circulation
  • people with anemia, a low red blood cell count. Many times, the anemia is caused by a low level of iron or folic acid in the person's body.
  • people with certain diseases and conditions, such as Parkinson's disease, rheumatoid arthritis, chronic renal failure, diabetes, and alcoholism
The symptoms of restless leg syndrome seem to be worsened by food and drinks that are high in caffeine.


What can be done to prevent the condition?

There is no reliable way to prevent restless leg syndrome. Controlling diseases and conditions that contribute to the syndrome can help limit the intensity of the symptoms. Reducing stress levels may also help decrease symptoms.


How is the condition diagnosed?

A complete history and physical examination is the first step in diagnosing restless leg syndrome. Often, a person will need tests to rule out other problems such as peripheral nerve disease and pain that results from poor circulation to the leg muscles.

Long Term Effects

What are the long-term effects of the condition?

The most common long-term effect of restless leg syndrome is difficulty sleeping. Insomnia can reduce a person's quality of life and also lead to other problems such as depression, violence, and motor vehicle crashes and other injuries..

Other Risks

What are the risks to others?

Restless leg syndrome is not contagious but does tend to run in families.


What are the treatments for the condition?

Treatment of restless leg syndrome begins with correction of any underlying disease or condition. For example, iron or folic acid supplements may be given to correct anemia. The healthcare professional will work with the person to treat other disorders such as rheumatoid arthritis, poor circulation to the legs, and diabetes.
Lifestyle changes may help relieve the intensity of the symptoms of restless leg syndrome. A balanced diet following the food pyramid may be supplemented with vitamins and iron. Food and drinks containing caffeine, such as coffee, tea, and chocolate, should be avoided.
Moderate exercise can contribute to better sleep habits. Because sleep is often disrupted in a person with restless leg syndrome, good sleep habits are important.
Some guidelines for good sleep include:
  • Choosing a cool, comfortable, quiet environment for sleep.
  • Going to bed at the same time every night.
  • Getting up at the same time every morning
While the symptoms of restless leg syndrome cannot be completely eliminated, some people get relief from:
  • relaxation techniques, such as biofeedback, yoga, or meditation
  • stress management
  • acupressure
  • walking or stretching
  • a hot or cold bath
  • hot or cold packs
  • massaging the legs
Certain medications, including levodopa/carbidopa (i.e., Sinemet), ropinirole (i.e., Requip), Pramipexole (i.e., Mirapex) or tranquilizers such as clonazepam (i.e., Klonopin) or lorazepam (i.e., Ativan), can also be helpful. Occasionally, low doses of narcotic pain medications, such as codeine or oxycodone, can help relieve the symptoms of restless leg syndrome.

Side Effects

What are the side effects of the treatments?

Side effects of the medications used to treat restless leg syndrome include stomach upset and allergic reaction to the medication. Drowsiness and difficulty concentrating are side effects of narcotics and tranquilizers. These medications can also be addictive. Levodopa/carbidopa may cause nausea, headache, and loss of appetite.

After Treatment

What happens after treatment for the condition?

Treatment of restless leg syndrome is lifelong. Often, the person can improve his or her quality of life by making appropriate lifestyle changes.


How is the condition monitored?

Restless leg syndrome is monitored through periodic visits to the healthcare professional to discuss symptoms and appropriate treatment. Any new or worsening symptoms should be reported to the healthcare professional.

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